Pharmaceutical production

Tube & Fitting

Tri-Clover UltraPure ASME BPE fittings

Fittings for pharmaceutical and biotech applications

Alfa Laval Tri-Clover UltraPure ASME BPE range includes a comprehensive selection of tubes and fittings of varying dimensions and executions all compliant with ASME BPE standards. Made for safe and easy installation, its high quality and good weldability meet the standards of biopharmaceutical industries.

Tubes & fittings account for 90% of product contact surfaces in a typical pharma application – ensure quality with Tri-Clover UltraPure ASME BPE

• Very low contamination risk – consistent, easy to clean internal surface finishes (electro or mechanically polished) with Ra of < 0.4 - 0.8μ
• Easy and safe installation – secure, self-aligning joints and smooth, crevice-free, corrosion-resistant interiors for guaranteed hygiene
• Reliability minimizes risk – incoming and outgoing raw material/product quality control and close monitoring of manufacturing process
• Integrity secured – tubes from the same material supplier ensure uniformity, high quality welds and assured chemical composition and passivity state
• Versatile – selection of tubes, bends, unions, clamps, reducers available in a range of surface finishes and dimensions

Optimize your processes and maximize uptime with Alfa Laval Tri-Clover UltraPure ASME BPE. Get fast access to replacement parts and service, readily available through our local offices and more than 1500 sales and working partners around the world. Whether you require single fittings, boxes, pallets or even containers directly from the

Inline Valve

Unique DV-ST UltraPure

Diaphragm valve for a range of duties including dosing, filling, diverting and controlling in aseptic or hygienic systems Alfa Laval Unique DV-ST UltraPure diaphragm valves are the natural choice for pharma and biotech industries (as well as other hygiene-focused processes). The compact and lightweight valves comprise a series of base parts including valve bodies, diaphragms, actuators and handles. The choice gives you a multitude of configurations to meet the exact needs of your process. All diaphragms used meet FDA/USP classifications as well as TSE/ADI.

High-quality valve bodies and wide range of proven diaphragms

• Reliable, long life diaphragm – available in high performance EPDM for continuous steam operation at temperatures up to 150 °C
• Reduced risk of contamination - fully documented, made for aseptic operation with standard low-ferrite valve body (option for high alloy solution)
• Simple and reliable stainless steel actuator with 5-year warranty – one-type-fits-all design makes selection safe, fast and easy
• Hygienic design – high-grade valve bodies and low Ra surface finishes
• Easy installation/validation/qualification and backed by Alfa Laval Q-doc comprehensive documentation package and service partner network

The actuator operates at up to 10 and 6 bar depending on diaphragm material (EPDM and PTFE/EPDM: 10 bar; TFM/PTFE: 6 bar). Autoclavability and chemical resistance ensure long service life and uptime. Over-closure protection (manual version) also helps prolong diaphragm life. All steel parts are made of stainless steel or composite material depending on handle type. There is also a range of easily mounted indication and control units

Unique Mixproof UltraPure

One valve providing double block and bleed with simplicity, safety and efficiency in mind - designed for the Pharmaceutical industry Alfa Laval Unique Mixproof UltraPure is designed to suit the needs of the Pharmaceutical and Biotech industries. It enables the simultaneous flow of two different fluids without the risk of cross-contamination. Modular in design, they ensure maximum uptime for continuous, high-purity processes.

The high-purity, double seat valve for continuous processes

• Non-spilling solution
• Easy to clean and maintain
• Modular design enables easy configuration
• Easy to upgrade

• Full component traceability The Alfa Laval Unique Mixproof UltraPure provides a higher degree of plant flexibility resulting in optimized plant efficiency without compromising product safety. </div>

  Unique Sampling Valve

  Superior hygienic sampling with patented double seat

  With Alfa Laval Unique Sampling Valves you can take representative samples in a variety of hygienic processes including food and beverage, personal care and biopharm. These reliable single and double-seat valves provide the high accuracy, exceptional reproducibility and excellent reliability required for high quality, cost-effective sampling. The ergonomically designed handle ensures exceptional control and convenience during operation.

Aseptic and sterilizable solution for safe sample collection

• Design ensures hygienic and contamination-free sampling
• Easy to operate thanks to simple working principle
• Highly reliable operation (rated to 10 bar) and three year warranty for all non-wearing parts
• Safe sampling through features such as non-return, quick couplings, pressure relief valve for steam and more
• Enhanced cleanability - valve body made of single piece of stainless steel provides smooth, crevice-free surfaces eliminating bacterial build-up risk

Certification, specification and standards: All Unique Sampling Valves are designed, tested and approved according to EHEDG guidelines and certified to carry the 3-A symbol. All product-wetted components are made of 1.4404 (316L). EN10204 3.1 included with valve.

Mixing Technology

LeviMag® UltraPure

The aseptic magnetic mixer for mixing down to the last drop in sterile process applications. Superior hygiene, optimized operation

The Alfa Laval LeviMag® UltraPure is an aseptic magnetic mixer that uses a patented levitating impeller and advanced design to mix down to the last drop and maximize product yield. Compact, energy-efficient and easy to maintain, it is perfect for biotech, pharmaceutical and demanding hygienic and sterile applications such as those involving serums, vaccines, plasma fractions, bacteria and cell cultures, and APIs.

• Optimized flow for higher efficiency and more gentle product treatment
• Mixing down to the last drop for maximum yield due to low agitation and dry-running capability
• Optimized Cleaning-in-Place thanks to full drainability
• Minimized downtime due to ease of maintenance
• Comprehensive documentation for full traceability of the entire supply chain

Maximize product yield and quickly realize return on investment due to the dry-running capability of the Alfa Laval LeviMag UltraPure magnetic mixer. Ensuring gentle product treatment is easy due to efficient mixing at very low speeds. The open design and low-speed rotation during cleaning contribute to no dead zones, effective residue removal and minimize contamination risks from wear particles

ALB

Bottom-mounted agitator for hygienic low maintenance mixing and blending in food, dairy, beverage and pharmaceutical applications

The Alfa Laval ALB bottom-mounted agitator is suitable for atmospheric and pressurized tanks and comes in a range of sizes. The modular design and choice of size ensures an agitator fit-for-purpose so you won’t have to invest more than needed and can look forward to optimal power consumption. The ALB agitators are designed for easy CIP and can also be for use in sterile/aseptic and ATEX-certified applications. Excellent levels of hygiene for a wide range of cost-effective, tank-based blending and mixing duties

• Easily tailored to meet specific tank/process requirements - modular design with hygienic materials increases flexibility and optimizes operation
• Reduced energy consumption – unique impeller design and product heat absorption makes ALB up to 400% more efficient than impellers with standard pitch
• Hygienic design and smooth surfaces meet EHEDG, USDA, FDA and 3-A standards
• Operates at low speeds without reducing pumping capacity – up to 80% less power consumption compared with conventional impellers
• High productivity – low wear and low maintenance (no dismantling or tank entry, for instance, to replace long-life seals and bearings)

We have versions for sterile/aseptic applications and optional equipment, including welding flange, blind flange, cover for motor/gear and spare part kit, for all ALB bottom-mounted agitators. ATEX certification and material certificates are available on request

ALT

Top-mounted agitator with free-hanging shaft for hygienic, low maintenance mixing and blending in food, dairy and pharmaceutical applications

The Alfa Laval ALT top-mounted agitator is suitable for atmospheric and pressurized tanks and comes in a range of sizes. The modular design and sizing options means you won’t have to invest more than needed and can look forward to optimal power consumption. ALT agitators are designed for easy CIP and can also be configured for use in sterile/aseptic and ATEX-certified applications.

Excellent levels of hygiene for a wide range of cost-effective, tank-based blending and mixing duties

• Easily tailored to meet specific tank/process requirements – modular design with hygienic materials increases flexibility and optimizes operation
• Reduced energy consumption – unique impeller design and product heat absorption makes ALT up to 400% more efficient than impellers with standard pitch
• Hygienic design and smooth surfaces meet EHEDG, USDA, FDA and 3-A standards
• Operates at low speeds without reducing pumping capacity – up to 80% less power consumption compared with conventional impellers
• High productivity – low wear and low maintenance (For instance, no dismantling or tank entry required to replace long-life seals and bearings)

We offer versions for sterile/aseptic applications and optional equipment, including welding flange, blind flange, cover for motor/gear and spare part kit, for all ALT top-mounted free-hanging agitators. ATEX certification and material certificates are

Hybrid Powder Mixer

Ideal for the dairy, food and beverage industries, this cost-effective dual-stage inline powder dissolution unit quickly mixes and pumps wet and dry ingredients into a homogeneous blend.

Innovative inline powder-liquid mixer

The Alfa Laval Hybrid Powder Mixer is a patented hygienic mobile and stationery unit that uses a single standard motor to disperse powders into liquids quickly and efficiently, and to pump the combined solution. By combining pump and powder dissolving technologies, this versatile, easy-to-use mixer produces homogeneous products at high productivity while delivering significant energy savings. Designed for batch production, it is the only inline powder mixer with a single motor drive that is able to disperse solids into liquids uniformly while simultaneously pumping the process liquid at pressures of up to 5 bar. It is an excellent choice for use in a wide variety of dairy, food and beverage powder mixing applications, such as dissolving stabilizers like pectin and xanthan gum and emulsifiers in the percentages required for most applications. It is also capable of producing recombined milk with more than 50% dry matter. In addition, when used in combination with an Alfa Laval Rotary jet mixer, the Hybrid Powder Mixer may also be used as part of an efficient cleaning-in-place (CIP) system

Pump

LKH UltraPure

Centrifugal pumps designed to meet the specific demands of pharmaceutical and biotech applications Alfa LKH UltraPure pharmaceutical pumps (certified to EHEDG) use a combination of optimised inlets and advanced impeller design to give unobstructed product flow, very low NPSH requirements and excellent hydraulic efficiency to keep your process running smoothly. They are designed for CIP and available in capacities of up to 500 m3/h and pressures of up to 190 m (19 bar).

Highly efficient and economical centrifugal pump that meets the requirements of hygienic processes

• Low contamination risk – hygienic design with pharma-grade SiC+ seals, pre-defined compression elastomers and low-delta ferrite impeller
• Maximized uptime and reduced maintenance costs – robust mechanical design and ease of maintenance with modular front-loading seals
• Increased yield – comes with full material traceability and USP Class VI elastomers to reduce risk of process contamination from extractables
• Energy and cleaning efficient – precise hydraulic design energy costs and CO2/waste chemical emissions to boost yields and process sustainability
• Smooth qualification, validation and process control – material traceability, and pump supplied with Alfa Laval’s Q-Doc package in line with GDP

The vane design of the semi-open impeller ensures a low Net Positive Suction Head required and prevents the effects of cavitation. The impeller balance holes help circulate the process fluid in the shaft seal area reducing axial force and wear on the seal and motor bearings. The high flow around the pump, especially behind the impeller near the shaft seal, makes cleaning easy and enhances the lubrication/ cooling of the seal to prolong life